Science In Sport Hydro Hydration Tablets, Gluten-Free, Zero Sugar, Orange Flavour Plus Electrolytes + Vitamin C, 20 Effervescent Tablets

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Recommended Usage: After prolonged or intense exercise use one tab in 500ml of water to support immune function as you rehydrate This approach gives you confidence that SIS pay attention to detail and deliver high quality sports nutrition, whether you are an elite athlete or just trying to keep fit and healthy You probably know by now that at SiS, we’re all about science. There is scientific evidence that health supplements work best when taken at particular times. For example, it is often recommended that you take multivitamin supplements in the morning as B Vitamins can be too stimulating for the brain before bed. Water soluble vitamins like B Vitamins and Vitamin C absorb best on an empty stomach, so you should take these around two hours prior to your meal or first thing in the morning. GET TOP TIPS FOR SPORTING PERFORMANCE AND NUTRITION ON OUR BLOG

Vitamin C (200mg) and Iron (2.5mg) are known to contribute to the maintenance of the normal function of the immune system during and after intense physical exercise in addition to your RDA. Supplementing can help you reach your fitness goals and enhance your overall well being. Our Performance Multivitamin is the perfect option for endurance athletes looking to meet their nutritional needs, with 19 key vitamins and minerals. These vitamins offer a multitude of benefits to your health, including supporting the normal functioning of the immune system, reducing tiredness and fatigue, maintenance of normal bones and muscle function, and normal protein and glycogen metabolism. SiS Immune dosage is designed to be at a level which supports athlete health without compromising training benefits In the form of an effervescent tablet, it makes into a low calorie rehydration drink containing vitamin C and IronThis depends on the type of exercise you’re doing. Whether it’s HIIT, endurance or strength training, the timing of your fuelling will differ. Generally, it’s a good idea to take your supplement just before your session if it’s high intensity, while long distance running or similar endurance exercise may benefit from intra workout supplementation. You could use energy powders, gels or even gummies during longer or more intense exercise sessions. The members of the Nod-like receptor (NLR) family can form multi-protein complexes called inflammasomes that regulate the secretion of pro-inflammatory cytokines like IL-1β [63]. IL-1β is a key mediator of inflammation and is known to be a major protective cytokine against S. aureus infection [64]. However, increased production of IL-1β can also aggravate GVHD pathophysiology [65]. Studies have identified different inflammasome pathways like Nlrp1, Nlrp3 and Ipaf. Apart from their role in infection, the inflammasomes have been linked to pyroptosis and autophagy [63]. Additionally, the Nlrp3 inflammasome is known to mediate the adjuvanticity of alum [66], [67]. The role of the inflammasome in wound healing is also becoming increasingly apparent [68]– [70]. Heavy training is known to impact the immune system, suppressing it for 3-72 hours post-training. This can lead to a higher incidence of upper respiratory tract Infections, impacting an athletes health and their ability to train. Excessive vitamin intake can suppress the training response. SiS Immune is designed to be at a level which supports athlete health without compromising training benefits. SiS Immune is tested under Informed Sport certification. This approach gives you confidence that we pay attention to detail and deliver high quality sports nutrition, whether you are an elite athlete or just trying to keep fit and healthy. After prolonged or intense exercise use one tab in 500ml of water to support immune function as you rehydrate.

Excessive vitamin intake can suppress the training response. SiS Immune is designed to be at a level which supports athlete health without compromising training benefits. As an effervescent tablet that readily dissolves in plain water, it represents a highly practical approach to support your immune system after exercise.Ingredients: Citiric Acid, Acidity Regulator (Sodium Hydrogen Carbonate, Sodium Carbonate), Sorbitol, Vitamin C (4.95%), Inulin, Natural Flavout, Starch, Tricalcium Phosphate, Sweetener (Sucralose), Maltodextrin, Natural Colour, Iron Sulphate (0.18%), Vitamin B12 (Riboflavin). Our Vitamin C tablets are fantastic for maintaining the normal function of your immune system and contribute to the reduction of tiredness and fatigue. Vitamins A, B, C, D and E are important for hair growth, alongside iron and zinc. HEALTH SUPPLEMENTS The use of mice has been guided by strict adherence to the protocols (ID# 09-15-2010:SKG/YA; ID# 01-03-2011: SKG/RR), approved specifically for this study, by the Indiana State University Animal Care and Use Committee (IACUC). Female BALB/c mice (6–8 weeks of age) were used for all experiments. Pathogen-free BALB/c mice were bought from Harlan Sprague-Dawley (Indiana, USA), kept in quarantine for two weeks and then relocated to specific mouse facility that is routinely monitored by veterinarians, IACUC and USDA inspectors. These mice were bred and maintained at the animal care facility of Indiana State University. The expression levels of CD30L, Eotaxin and Fractalkine are up-regulated due to the combined exposure of HKSA and SIS-H relative to SIS-H alone. All three of these molecules are known to promote graft rejections. Data for each group used in the figure are based on fold change values obtained by comparing to the PBS control group (*= p<0.05, **= p<0.01 and ***= p<0.001). A–C): Effect of HKSA-SIS-H exposure on the expression of inflammatory cytokines and chemokines involved in wound healing and GVHD. Data for each group used in the figure are based on fold change values obtained by comparing to the PBS control group. (*= p<0.05, **= p<0.01 and ***= p<0.001).